This morning I got the same error when attempting to run my web application. Before I restarted IIS, I went and looked at the application pools and there is no indication of any problems (they are all running). There is nothing in the event log relating to IIS, application pools, ASP.NET, etc. Does anyone have any suggestions of where I should continue to look? I'm kind of in a bind here and I don't know what to do next. Any help is appreciated. Thanks.