Hi,

Try this code-

Protected Sub ProjectGrid_ItemDataBound(sender As Object, e As DataGridItemEventArgs)
	If e.Item.ItemType = ListItemType.Item Then
		Dim spndropdown As HtmlGenericControl = DirectCast(e.Item.FindControl("spndropdown"), HtmlGenericControl)
		Dim spndropdownText As String = spndropdown.InnerHtml
		spndropdown.InnerHtml = "Select one"
		Dim AlternateDropDownList As HtmlGenericControl = DirectCast(e.Item.FindControl("AlternateDropDownList"), HtmlGenericControl)
		Dim strAlternateDropDownList As String = AlternateDropDownList.InnerHtml
		AlternateDropDownList.InnerHtml = "flag data"
	End If
End Sub
Protected Sub ProjectGrid_ItemCommand(source As Object, e As DataGridCommandEventArgs)
	If e.Item.ItemType = ListItemType.Item Then
		Dim spndropdown As HtmlGenericControl = DirectCast(e.Item.FindControl("spndropdown"), HtmlGenericControl)
		Dim AlternateDropDownList As HtmlGenericControl = DirectCast(e.Item.FindControl("AlternateDropDownList"), HtmlGenericControl)
	End If
End Sub