Refer to:

Dim b As New Button
b.Text = "Click"
AddHandler b.Click, AddressOf ButtonClick
Placeholder1.Controls.Add(b)

http://msdn.microsoft.com/en-us/library/y3bwdsh3.aspx#Y2132

What is the difference between what I have and the example on the above link which adds a button click (client-side) event to a button  added at run-time.