Hands on experience is definately the most important thing. However, the Microsoft certifications do give you a distinct advantage. About 2 weeks after I earned my MCDBA I was offered, and accepted, a job with a multi-national company. Along with the job came a pay raise of $15,000 per year. My new company has offered to help me get my MCAD certification (they will pay for everything. boot camp, testing, materials...). The best part of this whole deal is another pay increase after I earn my MCAD. Obvisouly, I am all for certifications.