Remember that the HyperlinkColumn can be found during the ItemDataBound Event. You are surely familiar with how to use this Event Handler, so I'll provide an example of code to use for the Item and Alternating ListItemTypes:
Private Sub dgrdProducts_ItemDataBound(ByVal sender As Object, ByVal e As DataGridItemEventArgs) Handles dgrdProducts.ItemDataBound
Dim item As ListItemType = e.Item.ItemType
If item = ListItemType.Item Or item = ListItemType.AlternatingItem Then
Dim hl As HyperLink = e.Item.Cells(0).Controls(0)
hl.NavigateUrl = "bogus.aspx?prodid=" & e.Item.DataItem("ProductID") & "&supplid=" & e.Item.DataItem("SupplierID")
End If
End Sub
The HL-Column is made up of Hyperlinks, so you'll need to find them. In my example, The first Control of the first Cell is a Hyperlink, as my Hyperlink Column is my First Column. You may now add as many arguments as you like to your hyperlink.