I would think that the easiest way would be to pull it from the database that way. Create a derived field from your database that takes the first 10 characters of your memo field.
The alternative would be to create a TemplateColumn that would take your memo field and truncate it in the GridView itself. Regardless of which you use, though, you will not have the whole field available to you from the GridView. If you plan to edit in the GridView, you will need to use the TemplateField approach and hide the full memo field in the ItemTemplate and show it in the EditItemTemplate, hiding your 10-character text.
If this isn't the direction you going in, please elaborate further.